drug discovery

Advancing AI for biology: Teaching models to design and characterize antibodiesamazon.science

Amazon Bio Discovery developed three AI models: MochiBind for fast, sequence-based antibody binding ranking, CA-MAP for context-aware developability prediction robust to batch effects, and an agent-guided system for de novo antibody design. These advancements aim to accelerate and improve the accuracy of antibody drug discovery, with experimental validation for a novel cancer target.