neuroscience

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Human brain is two separate organs, Stanford Medicine-led research finds stanford.edu
Stanford researchers discovered that the human brain develops from two separate progenitor lineages—one for forebrain/midbrain (Otx2) and one for hindbrain (Gbx2)—and used this insight to grow functional hindbrain neurons from pluripotent stem cells. This breakthrough provides a platform for studying brain‑stem diseases such as SMA and ALS and reshapes our understanding of brain evolution.
Hacker News front pagestanford.eduKrista Conger3d5 minreleaseHN654257
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Our brain evolved from two primitive nervous systems that merged: Study newscientist.com
A new study shows that the forebrain and hindbrain develop from distinct progenitor cells (OTX2‑expressing and GBX2‑expressing) in mouse, human, chicken, zebrafish and acorn worm embryos, suggesting the vertebrate brain originated from the merger of two primitive nervous systems over 550 M years ago. This insight enabled the first successful in‑vitro generation of human hindbrain motor neurons.
Hacker News front pagenewscientist.comAlice Klein4d3 minHN13275

Human brain is two separate organs, Stanford Medicine-led research findsstanford.edu