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HypoEvolve: Genetic Algorithms Enable Multi-Agent LLMs to Discover Scientific Hypotheses
The paper presents HypoEvolve, a generational genetic algorithm that coordinates specialized LLM agents to iteratively propose, critique, and refine scientific hypotheses. On a drug‑repurposing benchmark across 34 cancer types, it outperforms six baselines, achieving a DepMap selectivity of 0.171 versus 0.115.
Hugging Face Daily Papersarxiv.org1 minpaper